IL-17A Alters Human Cortical Development in a 3D Ex Vivo Model of Maternal Immune Activation
Muhammad Zaman Khan Assir, Mario Yanakiev, Do Hyeon Gim, Sara S. M. Valkila, Paola Muscolino, Liu Peng, Paul Fowler, Daniel A. Berg, Eunchai Kang
The paper shows IL-17A disrupts human cortical development in a 3D ex vivo model of maternal immune activation by altering neurogenesis and ECM pathways.
bioRxiv · Oct 30, 2024 · PreprintNeuroscience