Author

Muhammad Zaman Khan Assir

University of AberdeenORCID 0000-0002-8940-9747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Eunchai KangiD· 4 shared Daniel A. BergiD· 3 shared Paul FowleriD· 3 shared Do Hyeon GimiD· 2 shared Olivia SoperiD· 2 shared Sara S. M. ValkilaiD· 2 shared Bettina PlattiD· 1 shared Delia RamíreziD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersNeuroscience

Eunchai KangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DNA damage-induced senescence reshapes transcriptomic and functional landscape of human neural progenitor cells

Nisha Vincy Jose, Muhammad Zaman Khan Assir, Olivia Soper, Susan Janssens, Bettina Platt, Eunchai Kang

This study establishes a human in vitro model of DNA damage-induced senescence in neural progenitor cells and identifies senescence-associated transcriptomic and functional changes linked to hippocampal ageing and neurodegeneration.

bioRxiv · May 1, 2026 · PreprintNeuroscience

A Human Hippocampal Organoid Model with Sustained Neural Stem Cells Reveals State Shifts Under Glucocorticoid Stress

Olivia Soper, Muhammad Zaman Khan Assir, Delia Ramírez, Gabriella Crawford, Richard Gyuris, Sara S. M. Valkila, Laetitia L. Lecante, Peng Liu, Paul Fowler, J. Antonio González, Daniel A. Berg, Eunchai Kang

This study develops a human hippocampal organoid model that shows how glucocorticoid stress shifts neural stem cell states, reducing proliferation and promoting quiescence.

bioRxiv · Nov 3, 2025 · PreprintNeuroscience

Deciphering Cell-Type and Temporal-Specific Matrisome Expression Signatures in Human Cortical Development and Neurodevelopmental Disorders via scRNA-Seq Meta-Analysis

Do Hyeon Gim, Muhammad Zaman Khan Assir, Paul Fowler, Michael David Morgan, Daniel A. Berg, Eunchai Kang

bioRxiv · Feb 24, 2025 · PreprintNeuroscience

IL-17A Alters Human Cortical Development in a 3D Ex Vivo Model of Maternal Immune Activation

Muhammad Zaman Khan Assir, Mario Yanakiev, Do Hyeon Gim, Sara S. M. Valkila, Paola Muscolino, Liu Peng, Paul Fowler, Daniel A. Berg, Eunchai Kang

The paper shows IL-17A disrupts human cortical development in a 3D ex vivo model of maternal immune activation by altering neurogenesis and ECM pathways.

bioRxiv · Oct 30, 2024 · PreprintNeuroscience