Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACIT
Khoa Huynh, Katarzyna M. Tyc, Bruno Fernandes Matuck, Quinn T. Easter, Aditya Pratapa, Nikhil V. Kumar, Paola Pérez, Rachel J. Kulchar, Thomas J. F. Pranzatelli, Deiziane de Souza, Theresa M. Weaver, Xufeng Qu, Luiz Alberto Valente Soares, Marisa Dolhnokoff, David Erwin Kleiner, , Jinze Liu
The paper introduces TACIT, an unsupervised algorithm for cell type annotation in spatial biology, showing improved accuracy and scalability across multiple datasets and applications.
bioRxiv · May 31, 2024 · PreprintBioinformatics