Quinn T. Easter

The Immunoregulatory Architecture of the Adult Oral Cavity

This paper presents a single-cell and spatial proteotranscriptomic atlas of human oral tissues, identifying fibroblasts as key immunoregulatory hubs and revealing changes in disease states.

Exploring endothelial cell environments across organs in spatially resolved omics data

The paper analyzes endothelial cell environments across organs using spatially resolved omics data and provides an interactive tool for visualizing cell distances and neighborhoods.

CD38⁺ Endothelial Remodeling Defines Spatially Diverse Vasculopathy Programs in Rapidly Advancing Oral Inflammation

The paper identifies CD38⁺ endothelial remodeling as a spatially distinct vasculopathy feature in rapidly advancing oral inflammation using scRNA-seq and spatial proteomics.

Polybacterial Intracellular Macromolecules Shape Single-Cell Epikine Profiles in Upper Airway Mucosa

This study reveals how persistent intracellular bacterial macromolecules in mucosal epithelial cells drive inflammatory signaling, offering new insights into microbial-host interactions and their potential impact on inflammatory disease treatment and drug efficacy.

Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACIT

The paper introduces TACIT, an unsupervised algorithm for cell type annotation in spatial biology, showing improved accuracy and scalability across multiple datasets and applications.