Kevin M. Byrd

This paper presents a single-cell and spatial proteotranscriptomic atlas of human oral tissues, identifying fibroblasts as key immunoregulatory hubs and revealing changes in disease states.

This study shows Notch signaling stabilizes ciliary lengths in lung multiciliated cells, with environmental factors like M. tb infection altering this regulation.

The paper analyzes endothelial cell environments across organs using spatially resolved omics data and provides an interactive tool for visualizing cell distances and neighborhoods.

STARComm identifies spatially co-located receptor-ligand interactions in human tissues, revealing disease-specific modules linked to clinical outcomes and drug targets.

The paper identifies CD38⁺ endothelial remodeling as a spatially distinct vasculopathy feature in rapidly advancing oral inflammation using scRNA-seq and spatial proteomics.

SAME improves multimodal spatial omics integration by allowing topological disruptions during alignment, enhancing cell-type accuracy and revealing hidden biological insights.

This study reveals how persistent intracellular bacterial macromolecules in mucosal epithelial cells drive inflammatory signaling, offering new insights into microbial-host interactions and their potential impact on inflammatory disease treatment and drug efficacy.

This study analyzes immune cell dynamics in HPV-negative HNSCC using single-cell RNA sequencing to identify molecular signatures and communication patterns associated with disease progression.

The paper introduces TACIT, an unsupervised algorithm for cell type annotation in spatial biology, showing improved accuracy and scalability across multiple datasets and applications.