Author

Mark Bothwell

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alec S.T. SmithiD· 1 shared Allan I. LeveyiD· 1 shared Anna K. GreenwoodiD· 1 shared Aquene N. ReidiD· 1 shared Changho ChuniD· 1 shared David L. MackiD· 1 shared Gregory A. CaryiD· 1 shared Gregory W. CarteriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alec S.T. SmithORCID

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2 papers

Recent·Most cited

Kat5 cKO Biological Domain Signatures Align with Human Alzheimer Disease

Gregory A. Cary, Jessica E. Young, Shannon E. Rose, Harald Frankowski, Martin Darvas, Mark Bothwell, Suman Jayadev, Aquene N. Reid, Anna K. Greenwood, Allan I. Levey, Karina Leal, Gregory W. Carter, Jesse C. Wiley

The paper compares the transcriptome of Kat5 knockout mice to AD datasets, finding similar gene expression patterns and showing KAT5 localization in AD neurons.

bioRxiv · Sep 13, 2025 · PreprintNeuroscience

Interferon-gamma Elicits Pathological Hallmarks of ALS in Human Motor Neurons

Changho Chun, Jung Hyun Lee, Alec S.T. Smith, David L. Mack, Mark Bothwell, Paul Nghiem

This study shows that interferon-gamma exposure causes TDP-43 mislocalization and ALS-like pathology in human motor neurons.

bioRxiv · Nov 18, 2022 · PreprintNeuroscience