Paul Nghiem

The paper shows that B cells specific for viral oncoproteins in Merkel cell carcinoma tumors predict long-term disease control and enhance T cell responses.

The paper shows that Merkel cell carcinoma produces MIF, which supports CLL persistence through CD74 and CXCR4 activation, explaining why CLL blood counts normalize after MCC treatment.

This study shows that interferon-gamma exposure causes TDP-43 mislocalization and ALS-like pathology in human motor neurons.

FAUST is a new interpretable machine learning method for single-cell cytometry that discovers and validates T cell correlates of response to anti-PD-1 immunotherapy.

BayesSpace enhances spatial transcriptomics resolution and clustering, revealing tissue structures undetectable at lower resolutions.