Aquene N. Reid

This study shows that SORL1 deficiency in neurons alters synaptic protein interactions, causes hyperexcitability, and impairs synaptic plasticity, linking endosomal recycling defects to Alzheimer's disease pathogenesis.

This study develops 2D and 3D human in vitro neurovascular unit models to investigate microglial interactions with endothelial cells and their role in neurovascular function under inflammatory conditions.

The paper compares the transcriptome of Kat5 knockout mice to AD datasets, finding similar gene expression patterns and showing KAT5 localization in AD neurons.

This study shows that genetic risk variants in endolysosomal network genes correlate with endolysosomal dysfunction in neural cells in Alzheimer's disease.