Activation of NF-κB signaling by optogenetic clustering of IKKα and β
Alexandra Fischer, Markus M. Kramer, Miguel Baños, Merlin M. Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber
The paper develops optogenetic tools to cluster eGFP-tagged proteins and uses them to activate NF-κB signaling by clustering IKKα and IKKβ.
Advanced Biology · Jul 29, 2025Peer-reviewedSynthetic Biology