Author

Merlin M. Grimm

University of Freiburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Synthetic Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra FischeriD· 2 shared Bodo GrimbacheriD· 2 shared Manfred FliegaufiD· 2 shared Wilfried WeberiD· 2 shared Carsten BaltesiD· 1 shared Deqiang KongiD· 1 shared Franziska LautenschlägeriD· 1 shared Gerald RadziwilliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Alexandra FischerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Activation of NF-κB signaling by optogenetic clustering of IKKα and β

Alexandra Fischer, Markus M. Kramer, Miguel Baños, Merlin M. Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber

The paper develops optogenetic tools to cluster eGFP-tagged proteins and uses them to activate NF-κB signaling by clustering IKKα and IKKβ.

Advanced Biology · Jul 29, 2025Peer-reviewedSynthetic Biology

Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice

Alexandra Fischer, Hanah B. Robertson, Deqiang Kong, Merlin M. Grimm, Jakob Grether, Johanna Groth, Carsten Baltes, Manfred Fliegauf, Franziska Lautenschläger, Bodo Grimbacher, Haifeng Ye, Volkhard Helms, Wilfried Weber

This study tunes the material properties of transcription factor condensates to show their impact on gene expression levels in mammalian cells and mice.

Small · Apr 4, 2024Peer-reviewedSynthetic Biology