Author

Marley Realing

University of Wyoming

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

David W. DonleyiD· 2 shared Jason P. GigleyiD· 2 shared Jonathan H. FoxiD· 2 shared Cailin S. DeiteriD· 1 shared Reed Campbell· 1 shared Stephen Hersch· 1 shared Teal Jenkins· 1 shared Vanita Chopra· 1 shared

Activity by Year

2019-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

David W. DonleyORCID

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2 papers

Recent·Most cited

Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease

David W. Donley, Marley Realing, Jason P. Gigley, Jonathan H. Fox

The paper shows iron activates microglia and enhances IDO1 activity in HD mice, contributing to neurodegeneration via the kynurenine pathway.

PLoS ONE · May 14, 2021Peer-reviewedNeuroscience

Latent Toxoplasma gondii infection increases soluble mutant huntingtin and promotes neurodegeneration in the YAC128 mouse model of Huntington's disease

David W. Donley, Teal Jenkins, Cailin S. Deiter, Reed Campbell, Marley Realing, Vanita Chopra, Stephen Hersch, Jason P. Gigley, Jonathan H. Fox

This study shows that latent Toxoplasma gondii infection worsens neurodegeneration in YAC128 HD mice by increasing soluble mutant huntingtin and neurofilament light protein levels.

bioRxiv · Feb 15, 2019 · PreprintNeuroscience