GDF15 contributes to inflammasome-associated excessive mechanoresponses of hyperlipidemic PdL fibroblasts
Martin Baumbach, Annamaria Manzolillo, Faezeh Ghazvini Zadegan, Raushan Yeskendirova, Annika Döding, Christoph‐Ludwig Hennig, Ulrike Schulze‐Späte, Judit Symmank, Collin Jacobs
This study shows GDF15 regulates excessive mechanoresponses in hyperlipidemic PdL fibroblasts via inflammasome/pyroptosis pathways and nuclear signaling.
bioRxiv · Sep 1, 2026 · PreprintCell Biology