Author

Collin Jacobs

Düsseldorf University HospitalORCID 0000-0002-1617-8888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Judit SymmankiD· 2 shared Annamaria Manzolillo· 1 shared Annika DödingiD· 1 shared Christoph‐Ludwig HennigiD· 1 shared Faezeh Ghazvini Zadegan· 1 shared Katrin von Brandenstein· 1 shared Lisa Schuldt· 1 shared Martin Baumbach· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Judit SymmankORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 1, 2026

GDF15 contributes to inflammasome-associated excessive mechanoresponses of hyperlipidemic PdL fibroblasts

Martin Baumbach, Annamaria Manzolillo, Faezeh Ghazvini Zadegan…·Collin Jacobs

This study shows GDF15 regulates excessive mechanoresponses in hyperlipidemic PdL fibroblasts via inflammasome/pyroptosis pathways and nuclear signaling.

DOI 10.64898/2026.08.30.748125

humanbulk RNA-seq

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Molecular BiologyEpigeneticsPeer-reviewedJun 28, 2022

Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression

Lisa Schuldt, Katrin von Brandenstein, Collin Jacobs, Judit Symmank

This study shows that oleic acid reduces inflammation in stressed PdL fibroblasts by increasing H3Kac at the IL10 promoter, suggesting epigenetic modulation as a therapeutic target for obesity-related inflammation.

23 citations

humanATAC-seq

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