Chromatin regulator Kdm6b is required for the establishment and maintenance of neural stem cells in mouse hippocampus
Eugene Gil, Sung Jun Hong, David Wu, Dae Hwi Park, Ryan Nicholas Delgado, Martina Malatesta, Sajad Hamid Ahanger, Karin Lin, Saul Villeda, Daniel A. Lim
This study shows that Kdm6b is essential for establishing and maintaining neural stem cells in the mouse hippocampus, with loss of Kdm6b leading to defective neurogenesis and cognitive impairments.
bioRxiv · Feb 20, 2024 · PreprintNeuroscience