Epileptic responses in marmosets induced by knockdown of CREB Regulated Transcription Coactivator 1 (CRTC1)
Yuki Nakagami, Misako Komatsu, Ken Nakae, Masanari Otsuka, Junichi Hata, Hiroaki Mizukami, Hiroshi Takemori, Shin Ishii, Hideyuki Okano, Akiya Watakabe, Tetsuo Yamamori
This study shows that CRTC1 knockdown in marmosets leads to epileptic responses and abnormal cFOS expression, with associated neural activity changes and lesions.
bioRxiv · Sep 22, 2023 · PreprintNeuroscience