Hiroaki Mizukami

This study evaluates Src inhibitor efficacy in OSCC cell lines and shows additive effects with cisplatin, enabling reduced cisplatin doses.

This study shows that inserting the YY1 binding motif upstream of the Rep/Cap gene increases AAV vector yield and improves the empty/full capsid ratio without affecting infectivity.

This study shows that reducing Nav1.1 in the dorsal striatum increases hyperthermia-induced seizures more than in the neocortex or nucleus accumbens.

This study shows that reduced excitatory input to the nucleus accumbens due to Scn2a haploinsufficiency impairs sociability without affecting dopamine levels.

The paper identifies nucleus accumbens parvalbumin-expressing fast-spiking inhibitory neurons as critical for convulsive seizure generation in mice with STXBP1 or SCN2A mutations.

This study shows that GABA signaling in the optic nerve mediates experience-dependent myelination, with binocular deprivation having less impact than monocular deprivation.

This study investigates altered synaptic remodeling in an ASD marmoset model and shows oxytocin reduces clustered spine emergence.

This study shows that CRTC1 knockdown in marmosets leads to epileptic responses and abnormal cFOS expression, with associated neural activity changes and lesions.

This study maps prefrontal cortex circuits in marmosets, revealing distinct local and long-distance projection patterns and their implications for primate brain organization.