Author

Mason T. Myers

University of Michigan

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

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Ailong KeiD· 1 shared Chunyi HuiD· 1 shared Ki Hyun NamiD· 1 shared Macy L. LozeniD· 1 shared Xufei ZhouiD· 1 shared Yan ZhangiD· 1 shared Zhonggang HouiD· 1 shared

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1 shared paperBiochemistry

Ailong KeORCID

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Recent·Most cited

BiochemistryMolecular CellPeer-reviewedJan 21, 2024

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications

Chunyi Hu, Mason T. Myers, Xufei Zhou…·Ailong Ke

This study defines the DNA binding and cleavage mechanisms of Type I-C CRISPR-Cas3 using cryo-EM and identifies anti-CRISPR proteins that inhibit its activity in human cells.

27 citations

humanstructural biology

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