Proximity Interactome analyses unveil novel regulators of IRE1a canonical signaling
Simon Le Goupil, Céline Philippe, Hadrien Laprade, Mathéo Lode, Rachel Boniface, Diana Pelizzari‐Raymundo, Kurt Dejgaard, Gregor Jansen, Celia M. Limia, Claudio A. Hetz, Sayyed Jalil Mahdizadeh, Luc Négroni, Marc Aubry, Jean‐Ehrland Ricci, Leif Axel Eriksson, Éric Chevet
The paper identifies novel IRE1 interactors that regulate its RNase activity and stability, revealing new functions in the unfolded protein response.
bioRxiv · Oct 27, 2024 · PreprintBiochemistry