CLIC-dependent internalization of caveolin-1 to lysosomal vacuoles in response to osmotic regulation
Timothy H. Wong, Matheus F. Lima, Aditya Nagrath, Y. Lydia Li, Bharat Joshi, FuiBoon Kai, Ivan R. Nabi
The paper shows that caveolin-1 is internalized via CLIC-dependent endocytosis to lysosomal vacuoles in response to osmotic changes, defining a new recycling pathway for membrane buffering.
Cell Reports · May 23, 2026Peer-reviewedCell Biology