Spatial self-organization of cancer stem cell niches revealed by live single-cell imaging
Mathilde Brulé, Anaïs Horochowska, Emeline Fontaine, Raoul Torero Ibad, Flavie Woesteland, Marie Denoulet, Jean Pesez, Éric Adriaenssens, Robert‐Alain Toillon, Xuefen Le Bourhis, Benjamin Pfeuty, Chann H. Lagadec, François Anquez
The paper uses live single-cell imaging to show cancer stem cells form spatial niches and undergo reprogramming influenced by both lineage and cell-cell interactions.
Stem Cell Research & Therapy · Oct 27, 2025Peer-reviewedSystems Biology