Author

Chann H. Lagadec

Centre National de la Recherche ScientifiqueORCID 0000-0002-5182-2069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Anaïs HorochowskaiD· 1 shared Benjamin PfeutyiD· 1 shared Emeline FontaineiD· 1 shared Éric AdriaenssensiD· 1 shared Flavie WoestelandiD· 1 shared François AnqueziD· 1 shared Isabelle FournieriD· 1 shared Jean Pesez· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Anaïs HorochowskaORCID

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2 papers

Recent·Most cited

Spatial self-organization of cancer stem cell niches revealed by live single-cell imaging

Mathilde Brulé, Anaïs Horochowska, Emeline Fontaine, Raoul Torero Ibad, Flavie Woesteland, Marie Denoulet, Jean Pesez, Éric Adriaenssens, Robert‐Alain Toillon, Xuefen Le Bourhis, Benjamin Pfeuty, Chann H. Lagadec, François Anquez

The paper uses live single-cell imaging to show cancer stem cells form spatial niches and undergo reprogramming influenced by both lineage and cell-cell interactions.

Stem Cell Research & Therapy · Oct 27, 2025Peer-reviewedSystems Biology

Development of Molecular Digital Twins Based on Ambient Ionization Mass Spectrometry Imaging for Real-Time Application in Oncological Surgery

Yanis Zirem, Léa Ledoux, Nina Ogrinc, Laurine Lagache, Roland P. Bourette, Chann H. Lagadec, Paul Chaillou, Michel Salzet, Isabelle Fournier

The paper develops a machine-learning pipeline using mass spectrometry imaging to create molecular digital twins for real-time oncological surgery, enabling precise tumor margin delineation and bacterial strain prediction.

bioRxiv · Dec 8, 2024 · PreprintBioengineering