Raoul Torero Ibad

Experimental and mathematical models reveal that AMPK modulates circadian clock gene expression and period through NAD+-dependent regulation of Bmal1

The paper shows that AMPK modulates circadian clock period and Bmal1 expression through NAD+-dependent mechanisms, validated by experiments and mathematical modeling.

Spatial self-organization of cancer stem cell niches revealed by live single-cell imaging

The paper uses live single-cell imaging to show cancer stem cells form spatial niches and undergo reprogramming influenced by both lineage and cell-cell interactions.

Otx2 stimulates adult retinal ganglion cell regeneration.

This study shows OTX2 promotes both survival and axon regeneration of adult retinal ganglion cells in vitro and in vivo.

OTX2 non-cell autonomous activity regulates inner retinal function

The paper shows that OTX2 non-cell autonomous activity in the retina affects inner retinal function and causes reduced visual acuity without altering retinal structure or photoreceptor physiology.