A modular toolbox for the optogenetic deactivation of transcription
Philipp Muench, Matteo Fiumara, Nicholas T. Southern, Davide Martino Coda, Sabine Aschenbrenner, Bruno E. Correia, Johannes Gräff, Dominik Niopek, Jan Mathony
The paper introduces LOOMINA, an optogenetic system that deactivates transcriptional activation in response to blue light, offering high adaptability and compatibility with various effector proteins.
Nucleic Acids Research · Dec 2, 2024Peer-reviewedSynthetic Biology