Commensal taxa in gut microbiota limit antibiotic resistance during extended oral antibiotic use
Erika L. Cyphert, Chongshan Liu, Victoria T. Chu, Aditi Dubey, Minying Liu, Zhe Zhong, James R. Cockey, Eva C. González Díaz, Angie L. Morales, Jacob C. Nixon, Matthew Garcia, Susana Zeng, Sidhant Rohatgi, Joan Wong, Ritwicq Arjyal, , Christopher J. Hernandez
The paper tracks antibiotic resistance gene (ARG) dynamics in mice during long-term antibiotic treatment, finding that commensal bacteria reduce ARG burden by outcompeting resistant taxa.
bioRxiv · Aug 13, 2025 · PreprintMicrobiology