The chromatin modifiers SET-25 and SET-32 are required for initiation but not long-term maintenance of transgenerational epigenetic inheritance
Rachel M. Woodhouse, Gabriele Buchmann, Matthew Hoe, Dylan Harney, Jason K. K. Low, Mark Larance, Peter R. Boag, Alyson Ashe
This study shows that SET-25 and SET-32 are needed for establishing but not maintaining transgenerational epigenetic silencing in C. elegans, indicating distinct genetic steps in the process.
Cell Reports · Nov 1, 2018Peer-reviewedGenetics