Peter R. Boag

The RNA-binding activity of the TRIM-NHL protein NHL-2 is essential for miRNA-mediated gene regulation

This study shows that NHL-2's RNA-binding activity is essential for miRNA-mediated gene regulation in C. elegans, linking it to translational repression and miRISC complex function.

WormCat: an online tool for annotation and visualization of Caenorhabditis elegans genome-scale data

WormCat is a web-based tool for annotating and visualizing gene set enrichment in C. elegans datasets, identifying both known and novel biological categories.

The chromatin modifiers SET-25 and SET-32 are required for initiation but not long-term maintenance of transgenerational epigenetic inheritance

This study shows that SET-25 and SET-32 are needed for establishing but not maintaining transgenerational epigenetic silencing in C. elegans, indicating distinct genetic steps in the process.

Widespread cytoplasmic polyadenylation programs asymmetry in the germline and early embryo

The paper identifies GLD-2 mediated cytoplasmic polyadenylation targets in C. elegans and shows CCF-1 as the major deadenylase for maternal mRNA silencing.

The TRIM-NHL protein NHL-2 is a Novel Co-Factor of the CSR-1 and HRDE-1 22G-RNA Pathways

This study identifies NHL-2 as a co-factor in C. elegans germline 22G-RNA pathways and shows it regulates gene expression through RNA binding and stability.