Targeted Analysis of >1500 Plasma Proteoforms via Individual Ion Mass Spectrometry
Aniel Sánchez, Indira Plá, Katrina N. Peterson, Vincent White, Troy D. Fisher, Michael A. R. Hollas, Taojunfeng Su, Nhat Hoang Van Le, Claire Harrington, Paolo Cravedi, David N. Assis, Paola A. Barrios, Therese Elaine Banea, Daniela P. Ladner, Eleonora Forte, , Neil L. Kelleher
This paper introduces two plasma proteoform panels, PPA 526 and PPA 1514, using Individual Ion Mass Spectrometry to quantify proteoforms in human plasma with high reproducibility and disease discrimination capability.
bioRxiv · May 31, 2026 · PreprintBiochemistry