Eleonora Forte

Targeted Analysis of >1500 Plasma Proteoforms via Individual Ion Mass Spectrometry

This paper introduces two plasma proteoform panels, PPA 526 and PPA 1514, using Individual Ion Mass Spectrometry to quantify proteoforms in human plasma with high reproducibility and disease discrimination capability.

Next-Generation Protein Sequencing and individual ion mass spectrometry enable complementary analysis of interleukin-6

This study compares single-molecule protein sequencing and individual ion mass spectrometry to analyze IL-6 proteoforms, showing combined coverage of 52% of the sequence.

Evaluation of Methodologies in Anti-nephrin Autoantibody Detection

The paper evaluates different methodologies for detecting anti-nephrin autoantibodies and finds that combined methods yield the most reliable results, with only two positive cases identified among 127 samples.

Cellular and Molecular Resolution of Focal Segmental Glomerulosclerosis Recurrence in Human Allografts

This study uses snRNA-seq to analyze kidney transplant biopsies and identifies molecular and cellular mechanisms of recurrent FSGS, including podocyte loss and PEC dedifferentiation.

Top-Down Proteomics Identifies Plasma Proteoform Signatures of Liver Cirrhosis Progression

This study uses top-down proteomics to identify plasma proteoform signatures that distinguish stages of liver cirrhosis progression.