Taojunfeng Su

This paper introduces a top-down mass spectrometry workflow with DMTm technology and a new software platform to achieve deeper proteoform sequencing and improved sequence coverage.

This paper introduces two plasma proteoform panels, PPA 526 and PPA 1514, using Individual Ion Mass Spectrometry to quantify proteoforms in human plasma with high reproducibility and disease discrimination capability.

This paper introduces Nuc-MS, a method to directly analyze chromatin reader-nucleosome interactions by disassembling complexes and identifying histone proteoforms involved in binding.

This study uses I2MS to analyze phosphorylation states of catenins in HEK cells, revealing their regulation by actomyosin contractility and identifying a phospho-code model for mechano-transduction.

This study compares single-molecule protein sequencing and individual ion mass spectrometry to analyze IL-6 proteoforms, showing combined coverage of 52% of the sequence.

This study shows replication stress reduces CENP-A nucleosome stability in S phase by disrupting ATRX and DAXX function, leading to centromere instability.