Large portion of essential genes is missed by screening either fly or beetle indicating unexpected diversity of insect gene function
Muhammad Salim Hakeemi, Salim Ansari, Matthias Teuscher, Matthias Weißkopf, Daniela Großmann, Tobias Kessel, Jürgen Dönitz, Janna Siemanowski, Xuebin Wan, Dorothea Schultheis, Manfred Frasch, Siegfried Roth, Michael Schoppmeier, Martin Klingler, Gregor Bucher
The paper expands an RNAi screen in Tribolium castaneum to assess gene function diversity between beetles and flies, finding that 50% of functions are shared while others are specific to one species.
bioRxiv · Feb 3, 2021 · PreprintGenetics