Dorothea Schultheis

This study examines how desmin mutations affect filament assembly and aggregation, finding that specific mutations disrupt filament maturation and lead to distinct aggregation pathways.

This study uses R405W desmin knock-in mice to identify mitochondrial dysfunction, protein quality control issues, and myofibrillar structural changes in myofibrillar myopathy.

The paper expands an RNAi screen in Tribolium castaneum to assess gene function diversity between beetles and flies, finding that 50% of functions are shared while others are specific to one species.

The paper identifies F-BAR proteins as critical for myoblast fusion and midgut morphogenesis in insects through RNAi screening in Tribolium.

The paper reports a large-scale RNAi screen in Tribolium castaneum identifying novel genes involved in insect muscle development, with results showing both shared and distinct genes compared to Drosophila.