4q-D4Z4 chromatin architecture regulates the transcription of muscle atrophic genes in FSHD
Alice Cortesi, Matthieu Pesant, Shruti Sinha, Federica Marasca, Eleonora Sala, Francesco Gregoretti, Laura Antonelli, Gennaro Oliva, Chiara Chiereghin, Giulia Soldà, Beatrice Bodega
The paper shows that the 4q-D4Z4 chromatin architecture regulates muscle atrophy gene transcription in FSHD by altering 3D nuclear contacts and chromatin states.
Genome Research · Jun 1, 2019Peer-reviewedGenomics