Early Polycomb-target deregulations in Hutchinson-Gilford Progeria Syndrome revealed by heterochromatin analysis
Endre Sebestyén, Fabrizia Marullo, Federica Lucini…·Chiara Lanzuolo
The paper identifies early chromatin structural changes in HGPS using a new method, showing Polycomb target gene deregulation linked to lamin-associated domain disruption.