Mitochondrial clone tracing within spatially intact human tissues
Sydney A. Bracht, Jiazhen Rong, Rodrigo A. Gier, Maureen DeMarshall, Hailey Golden, Diya Dhakal, Jayne C. McDevitt, Feiyan Mo, Emma Elizabeth Furth, Alexandra L. Strauss, Amanda B. Muir, Gary W. Falk, Bryson W. Katona, Ben Z. Stanger, Nancy Ruonan Zhang, Sydney M. Shaffer
SUMMIT traces mitochondrial mutations in human tissues to identify spatially localized clones and their transcriptomic profiles.
bioRxiv · Jul 11, 2025 · PreprintGenomics