Raúl A. Reyes Hueros

This study uses dynamic caging to link live-cell behavior with transcriptional responses across perturbations, revealing new insights into immune and inflammatory gene regulation.

The paper identifies non-genetic factors influencing proliferation variability in esophageal epithelial clones using clonal tracing and scRNA-seq.

The paper develops a method to quantify gene expression memory and identify regulators of cell state transitions, showing that modulating PI3K and TGF-β pathways can reduce drug resistance in melanoma.

The paper identifies clonal cell states in Barrett's esophagus and links them to esophageal adenocarcinoma progression through single-cell lineage tracing and transcriptional profiling.

The paper introduces MemorySeq, a method to identify gene expression fluctuations persisting across cell divisions, revealing non-genetic, heritable cellular behaviors in cancer cell lines.