Crosstalk of the MAP3K1 and EGFR pathways mediates gene-environment interactions that disrupt developmental tissue closure
Jingjing Wang, Bo Xiao, Eiki Kimura, Maureen Mongan, Wei-Wen Hsu, Mario Medvedovic, Alvaro Puga, Ying Xia
The paper investigates how dioxin interacts with genetic factors in Map3k1+/- mice to disrupt embryonic eyelid closure through MAP3K1 and EGFR pathway crosstalk.
bioRxiv · Mar 14, 2024 · PreprintDevelopmental Biology