Crosstalk of the MAP3K1 and EGFR pathways mediates gene-environment interactions that disrupt developmental tissue closure
Jingjing Wang, Bo Xiao, Eiki Kimura…·Ying Xia
The paper investigates how dioxin interacts with genetic factors in Map3k1+/- mice to disrupt embryonic eyelid closure through MAP3K1 and EGFR pathway crosstalk.