Primary cilium-dependent cAMP/PKA signaling at the centrosome regulates neuronal migration
Julie Stoufflet, Maxime Chaulet, Mohamed Doulazmi, Coralie Fouquet, Caroline Dubacq, Christine Métin, Sylvie Schneider‐Maunoury, Alain Trembleau, Pierre Vincent, Isabelle Caillé
The paper shows that primary cilia regulate neuronal migration through cAMP/PKA signaling at the centrosome, with genetic and imaging experiments demonstrating the role of ciliary Adenylate Cyclase 3 and centrosomal PKA.
Science Advances · Sep 2, 2020Peer-reviewedNeuroscience