Photothrombosis induced cortical stroke produces electrographic epileptic biomarkers in mice
Dana C. Shaw, Krishnakanth Kondabolu, Katherine G. Walsh, Wen Shi, Enrico Rillosi, Maxine Hsiung, Uri T. Eden, Robert Mark Richardson, Mark Kramer, Catherine J. Chu, Xue Han
This paper introduces a photothrombotic stroke model in mice that reproduces human epilepsy electrographic biomarkers, showing increased spike ripples and delta power in the stroke hemisphere.
bioRxiv · Mar 1, 2024 · PreprintNeuroscience