Long-term mitigation of the foreign-body response with dexamethasone-eluting cochlear implants in mice
Aditya Alluri, Bryce Hunger, md Fahad Hossain, Shakila Mahmuda Fatima, Muhammad Taifur Rahman, Brian J. Mostaert, Robert D. Gay, Ya Lang Enke, Marlan Rex Hansen, Alexander D. Claussen
This study shows dexamethasone-eluting cochlear implants reduce and sustainably suppress the foreign-body response in mice over 336 days, with reduced fibrosis and immune infiltration.
bioRxiv · Sep 1, 2026 · PreprintNeuroscience