Marlan Rex Hansen

Establishment of a cochlear lymphatic vascular network and immune surveillance system following cochlear implantation

This study identifies a lymphatic vascular network and immune surveillance system in the cochlea following implantation, contributing to inflammatory responses.

Long-term mitigation of the foreign-body response with dexamethasone-eluting cochlear implants in mice

This study shows dexamethasone-eluting cochlear implants reduce and sustainably suppress the foreign-body response in mice over 336 days, with reduced fibrosis and immune infiltration.

Presynaptic CaV2.1 calcium dependent facilitation is essential for faithful auditory information transfer

The paper investigates the role of CaV2.1 calcium-dependent facilitation in auditory synaptic transmission, finding that its absence reduces synaptic reliability and precision.

Supervised Automation of Cell Counting in Confocal Microscopic Cochlear Imaging Datasets Using Macro in Imaris

The paper develops a supervised automation protocol in Imaris to streamline cell counting in confocal cochlear images, reducing manual effort and human error.

Neural correlates of individual differences in speech-in-noise performance in a large cohort of cochlear implant users

The paper identifies neural correlates of speech-in-noise performance in cochlear implant users using EEG and clinical speech tests, finding ERP amplitudes predict word recognition tasks better than traditional measures.

Chronic Cochlear Implantation with and without Electric Stimulation in a Mouse Model Induces Robust Cochlear Influx of CX3CR1+/GFP Macrophages.

This study shows chronic cochlear implantation, not electric stimulation, drives macrophage infiltration and fibrosis in mice, with surgical trauma initiating the immune response.

NeuriteNet: A Convolutional Neural Network for determining morphological differences in neurite growth

NeuriteNet is a CNN that sorts neuronal images into control and treatment groups based on morphological differences and highlights distinguishing features via saliency maps.