Conditional Localization Pharmacology Manipulates Cell Cycle with Spatiotemporal Precision
Changfeng Deng, Yung-Chi Lan, Geng-Yuan Chen, Chigozie S. Ekeabu, Quoc Doan, Megan Chung, Michael A. Lampson, David M. Chenoweth
This paper introduces a method to control kinase activity with spatiotemporal precision using conditional localization pharmacology, demonstrating its ability to manipulate the cell cycle.
Journal of the American Chemical Society · Feb 9, 2026Peer-reviewedPharmacology & Toxicology