Michael A. Lampson

The paper shows that satellite DNA composition affects PRC1-mediated heterochromatin formation and mitotic spindle interactions in early embryos.

The paper investigates how centromeric satellite array size asymmetry affects meiotic function in mice, finding that small arrays paired with larger ones lead to chromatin and spindle defects and increased aneuploidy.

The paper shows that HMGA2 abundance and major satellite copy number are reciprocally constrained in mouse meiosis, with each affecting the other's stability.

This paper introduces a method to control kinase activity with spatiotemporal precision using conditional localization pharmacology, demonstrating its ability to manipulate the cell cycle.

The paper shows that microtubule depolymerization at kinetochores limits spindle elongation rather than moving chromosomes apart during anaphase.

The paper shows that telomere length inheritance in mice depends on a parent-of-origin effect during early embryonic telomere elongation, with molecular signatures of the ALT pathway involved.

The paper shows that the selfish element R2d2 in mice uses a hybrid mechanism in female meiosis to distort transmission by causing aneuploidy in the egg, leading to increased transmission of R2d2.

The paper describes a novel centromere structure in the mouse species Mus pahari, characterized by a divergent repeat and unique CENP-B recruitment, enabling high-fidelity segregation during cell division.

The paper tracks CENP-A dynamics in mouse gametes and embryos, showing sex-specific differences in centromere maintenance and equalization during early development.