NeuroscienceJCI InsightPeer-reviewed
Neurofilament accumulation disrupts autophagy in giant axonal neuropathy
Jean‐Michel Paumier, James P. Zewe, Chiranjit Panja…·Puneet Opal
This paper shows that neurofilament accumulation in GAN disrupts autophagy through impaired organelle distribution and sequestration of 14-3-3, affecting TFEB localization.
7 citations