Microglia and macrophages alterations in the CNS during acute SIV infection: a single-cell analysis in rhesus macaques
Xiaoke Xu, Meng Niu, Benjamin G. Lamberty, Katy M. Emanuel, Shawn Ramachandran, Andrew J. Trease, Mehnaz Tabassum, Jeffrey D. Lifson, Howard S. Fox
This study uses single-cell RNA sequencing to analyze microglia and macrophages in rhesus macaques during acute SIV infection, revealing changes in cell clusters and gene expression linked to inflammation and neurodegeneration.
PLoS Pathogens · Sep 16, 2024Peer-reviewedMicrobiology