Mitochondria-ER contacts restrain store-operated Ca{superscript 2}⁺ entry via Ca{superscript 2}⁺ flickering and STIM1 trapping
Yu-Chiao Lin, Chieh-Ju Sung, Yu-Chun Lin, Hsuan-Chao Lin, Pei-Ju Tsai, Mei-Leng Cheong, Feng‐Chiao Tsai
This study shows that mitochondria-ER contacts inhibit store-operated Ca²⁺ entry by trapping STIM1 through Ca²⁺ flickering and microdomain formation.
bioRxiv · Jan 17, 2025 · PreprintCell Biology