Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle.
John Lian, Ryan G. Walker, Andrea D’Amico, Ana Vujić, Melanie J. Mills, Kathleen A. Messemer, Kourtney R. Mendello, Jill M. Goldstein, Krystynne A Leacock, Soraya Epp, Emma V. Stimpfl, Thomas B. Thompson, Amy J. Wagers, Richard Theodore Lee
The paper investigates the functional differences between GDF11 and GDF8 by substituting amino acids and identifies distinct effects on skeletal development and muscle.
Life Science Alliance · Jan 11, 2023Peer-reviewedDevelopmental Biology