Author
Harvard University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Bryan L. Peacker, Kuan‐Hung Lin, Amy Lam…·Amy J. Wagers
This study demonstrates CRISPR-HDR efficiency in postnatal cardiac, skeletal muscle, and muscle stem cells, showing developmental stage-dependent HDR rates and successful correction of a Dmd mutation in mdx mice.
Kuan‐Hung Lin, Amy Lam, Samual Ooijen…·Amy J. Wagers
This study demonstrates that single-vector adenine base editing via MyoAAV can recode a DMD-causing mutation in mice, with optimal therapeutic outcomes achieved in juvenile animals.
Vera D. Rinaldi, Kathleen A. Messemer, Kathleen Desevin…·Oliver J. Rando
The paper shows that Cre recombinase can be transported from somatic tissues to the male reproductive tract in mice, suggesting inter-tissue RNA or protein trafficking.
John Lian, Ryan G. Walker, Andrea D’Amico…·Richard Theodore Lee
The paper investigates the functional differences between GDF11 and GDF8 by substituting amino acids and identifies distinct effects on skeletal development and muscle.