Author

Melanie Vollstedt

Christian-Albrechts-Universität zu Kiel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alexander HerbigiD· 1 shared André FrankeiD· 1 shared Anja FurtwängleriD· 1 shared Aya K.H. MahdyiD· 1 shared Ben Krause‐KyoraiD· 1 shared Corinna BangiD· 1 shared Ella ReiteriD· 1 shared Érika Endo Kokubun· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Alexander HerbigORCID

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2 papers

Recent·Most cited

Quantifying The Impact of Bulk TCR-Seq Methodological Choices on The Profiled T Cell Repertoire

Aya K.H. Mahdy, Janina Fuß, Sören Franzenburg, Melanie Vollstedt, Yewgenia Dolshanskaya, Érika Endo Kokubun, Valeriia Kriukova, Florian Tran, Corinna Bang, Marte Lie Høivik, Jurgita Skiecevičienė, Juozas Kupčinskas, Mathilde Poyet, André Franke, Hesham ElAbd

This study evaluates how methodological choices in bulk TCR-Seq affect T cell repertoire profiling, finding that RNA/DNA quality significantly impacts results and that low quantities can be partially compensated by increasing PCR cycles.

bioRxiv · Aug 5, 2025 · PreprintImmunology

Comparison of target enrichment strategies for ancient pathogen DNA

Anja Furtwängler, Judith Neukamm, Lisa Böhme, Ella Reiter, Melanie Vollstedt, Natasha Arora, Pushpendra Singh, Stewart Thomas Cole, Sascha Knauf, Sébastien Calvignac‐Spencer, Ben Krause‐Kyora, Johannes Krause, Verena J. Schuenemann, Alexander Herbig

This study compares three DNA enrichment methods for ancient pathogen DNA, finding in-solution approaches are most effective and RNA baits outperform DNA baits.

BioTechniques · Nov 2, 2020Peer-reviewedGenetics