Maresin-1 promotes neuroprotection and prevents disease progression in experimental models of multiple sclerosis through metabolic reprogramming and shaping innate and adaptive disease-associated cell types
Insha Zahoor, Mohammad Nematullah, Mohammad Ejaz Ahmed, Mena Fatma, Mir Sajad, Kamesh Ayasolla, Mirela Cerghet, Suresh S. Palaniyandi, Veronica Ceci, Giulia Carrera, Fabio Buttari, Diego Centonze, Yang Mao‐Draayer, Ramandeep Rattan, Valerio Chiurchiù, Shailendra Giri
This study shows that MaR1 treatment reduces inflammation, protects neurons, and improves metabolism in a mouse model of multiple sclerosis.
bioRxiv · Sep 25, 2023 · PreprintImmunology